Workflows

High-level association analysis entry points.

associate$regression() fits one or more association models between observation-side clinical or biological endpoints and predictors resolved from a PolyGeniusData object.
Aliases: associate-regression, associate.regression, associate$regression
associate$mediation() estimates total, direct, and indirect effects for a specified exposure-mediator-outcome triplet resolved from a PolyGeniusData object.
Aliases: associate-mediation, associate.mediation, associate$mediation
associate$mr() declares the Mendelian-randomization surface for PolyGenius. The function validates the requested inputs, but no MR estimator backend is currently implemented.
Aliases: associate-mr, associate.mr, associate$mr
associate$meta() pools summary-mode association results across studies or cohorts. The function consumes one or more PolyGeniusAssociations objects with a shared schema and pools only their inferential summary rows.
Aliases: associate-meta, associate.meta, associate$meta
associate$compare() runs formal comparison workflows on observation-side data resolved from a PolyGeniusData object.
Aliases: associate-compare, associate.compare, associate$compare